ABGC final review (100% Errorless Answers)
Gail Model Pros correct answers Lifetime and 5-year breast cancer risk
Determine eligibility to take chemoprevention
Includes age, age at first live birth, age at menarche, # of FDR with BC, breast biopsy, atypical hyperplasia, race
Gail model cons correct answers NOT used for women with LCIS/DCIS
No other cancers
Does not consider SDR
Does not consider paternal history
Does not consider age of onset for cancers
Underestimates risk
Claus Tables correct answers Calculate BC risk based on family history of breast cancer only
Breast cancer prior probability models correct answers BRCAPro
Penn II
BOADICEA
Tyler-Cuzick
Myriad
High penetrance breast cancer genes correct answers BRCA1: 20-30%
BRCA2: 10-20%
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