Analgesics Questions And Answers
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1. WHO analgesic
ladder
Stepwise approach to pain management with increasing
drug potency
Step 1:non-opioid plus optional adjuvant analgesics for
mild pain
Step 2: weak opioid plus non-opioid and adjuvant analgesics for mild to moderate pain
Step 3: strong opioid plus non-opioid and adjuvant analgesics for moderate to severe pain
2. Adjuvant Substance that increases the immune response to antigens
3. Opiates opium and its derivatives, such as morphine and heroin;
they depress neural activity, temporarily lessening pain
and anxiety
Natural
4. Opioids All natural, semisynthetic and synthetic opioids
5. where do analgesics work?
Brain and spinal cord
6. NSAIDs Non-Steroidal Anti-Inflammatory Drugs that inhibit COX
enzymes
7. Coxibs Specific type of NSAIDs that selectively inhibit COX-2
8. Paracetamol Analgesic and antipyretic drug without anti-inflammatory
properties
9. Opioids Strong pain relievers that act on opioid receptors
10. Activation of descending noradrenergic and/or
5HT systems
Process that leads to the activation of spinal inhibitory
interneurons
11. Enkephalins Endogenous opioids released by spinal inhibitory interneurons as neurotransmitters