1.The nurse is reviewing medication information with a nursing student prior to

administeringan oral drug and notes that the drug has extensive first-pass effects. Which

statement by the student indicates a need for further teaching about this medication?

a. "The first-pass effect means the drug may be absorbed into systemic circulation

from the intestinal lumen."

b. "The first-pass effect means the drug may be changed to an inactive form and excreted."

c. "The first-pass effect means the drug may be changed to a metabolite, which may be

more active than the original."

d. "The first-pass effect means the drug may be unchanged as it passes through the liver."

2.The nurse is preparing to administer a drug and learns that it binds to protein at a rate of

90%. The patient's serum albumin level is low. The nurse will observe the patient for

a. decreased drug absorption.

b. decreased drug interactions.

c. decreased drug toxicity.

d. increased drug effects.

3.A nurse is preparing to administer an oral drug that is best absorbed in an acidic

environment. How will the nurse give the drug?

a. On an empty stomach

b. With a full glass of water

c. With food

d. With high-fat food

4.The nurse is preparing an injectable drug and wants to administer it for rapid absorption.

How will the nurse give this medication?

a. IM into the deltoid muscle

b. IM into the gluteal muscle

c. SubQ into abdominal tissue

d. SubQ into the upper arm

5.The nurse is administering two drugs to a patient and learns that both drugs are

highlyprotein-bound. The nurse may expect

a. decreased bioavailability of both drugs.

b. decreased drug effects.

c. decreased drug interactions.

d. increased risk of adverse effects.

6.The nurse gives a medication to a patient with a history of liver disease. The nurse will

monitor this patient for

a. decreased drug effects.

b. increased drug effects.

c. decreased therapeutic range.

d. increased therapeutic range.

7.The nurse gives 800 mg of a drug that has a half-life of 8 hours. How much drug will be

leftin the body in 24 hours if no additional drug is given?

a. None

b. 50 mg

c. 100 mg

d. 200 mg

8.The nurse is preparing to administer a drug that is ordered to be given twice daily. The nurse

reviews the medication information and learns that the drug has a half-life of 24 hours. What

will the nurse do next?

a.Administer the medication as ordered.

b.Contact the provider to discuss daily dosing.

c.Discuss every-other-day dosing with the provider.

d.Hold the medication and notify the provider.