Regarding antipsychotics as a group

a. Metabolites are important to the action of these drugs

b. Haloperidol has a higher systemic availability than thioridazine or

chlorpromazine

c. Elimination half lives of these drugs range between 3 – 6 hours

d. This group of drugs generally has short clinical duration of action

e. Clozipine is a member of the dihydroindolone group

2. Which of the following antipsychotics (in excess dose) is responsible for

cardiac arrhythmias?

a. Chlorpromazine

b. Clozapine

c. Thioridazine

d. Haloperidol

e. Thiothixene

3. Plasma lithium levels (assuming no change in daily lithium dose) may become

toxic in the presence of all of the following EXCEPT

a. Pregnancy

b. Use of thiazides

c. Dehydration

d. Use of some non-steroidal anti-inflammatory drugs

e. Post partum state

4. Regarding pharmacokinetics of antidepressants

a. Most are highly protein bound

b. Fluoxetine is poorly absorbed

c. Tricyclics are predominantly excreted unchanged in the urine

d. Plasma half lives of antidepressants are mostly less than 10 hours

e. The half life of the older MAOIs is helpful in governing doses

5. Which of the following drugs is potentially dangerous in a single drug

overdose

a. Moclobemide

b. Paroxetine

c. Sertraline

d. Trazodone

e. Amoxapine