Ceftriazone (Rocephin)

• broad spectrum cephalosporin

Ceftriazone (Rocephin) drug-drug interactions

• Piperacillin sodium; Clients with allergies to piperacillin sodium, a

penicillin, may have a cross-sensitivity to Ceftriaxone, a thirdgeneration cephalosporin. This should be reported to the primary care

provider.

Onset time for IV route

• 10-15 minutes

What is the preferred site for heparin injection?

• Subcutaneous tissue of the abdomen

Gemfibrozil (Lopid)

• Monitor periodically liver function; Gemfibrozil (Lopid) is converted by

the liver to active metabolites, and therefore, it is necessary to

undergo periodic liver function studies to monitor for active hepatic

disease or elevated transaminase levels.

What follow up diagnostic test would be necessary for an individual on

valproic acid (Depakene)?

• Platelet count, aspartate aminotransferase (ASTL), and alanine

aminotransferase (ALT)

Chlorothiazide (Diuril) and digoxin (Lanoxin)...monitor for what?

• Muscle weakness; The client is at risk for hypokalemia due to fluid loss

from chlorothiazide, which places him at greater risk for digoxin

toxicity. Muscle weakness is a sign of hypokalemia.

What is the indicated action of lactulose (Cephulac)?

• To reduce serum ammonia levels

diphenoxylate and atropine (Lomotil) monitor what what?