● Animal Development
○ Fertilization
■ The function of the cortical granules in relation to the vitelline envelope and plasma
membrane
○ Preventing polyspermy
■ Acrosomal enzymes eat away at the membrane
■ FAST block: species receptors change the membrane electrical potential by binding to
the bindin proteins on the acrosome...
● Na+ released into the cell making it positively charged
■ Fuse egg and sperm together → Ca+ wave to initiate slow bock
■ SLOW block: cortical granules fuse with membrane, goes back to negatively charged,
enzymes break connection between membrane and vitelline envelope, envelope
hardens & no bindin proteins for other sperm
■ Egg and sperm nuclei fuse → diploid zygote
○ Cleavage: embryo divides repeatedly into a small cluster of cells forming blastomeres (blastula)
■ Patterns of Yolk Distribution
● Holoblastic → whole embryo is dividing
○ Isolecithal → equal yolk distribution, most easily cleaved
■ Radial → new cells directly on top of each other forming new
layers
● Regulative development - new organism
■ Spiral → new cells form in furrows that are packed tightly
● Mosaic development - NO new organism
○ Mesolecithal → moderate distribution of yolk
■ Radial
● Meroblastic → part of the egg yolk remains undivided cluster of cells divide on
top of the yolk
○ Telolecithal → yolk concentrated at vegeta pole
○ Centrolecithal → large centrally located mass of yolk, most likely complete
cleavage
○ Blastulation: cleavage of the cytoplasm
○ Gastrulation: formation of germ layers & coelom by invagination
■ Germ Layers (outer to inner)
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