1 antibody screening cell positive and 1 donor positive in AHG - CORRECT ANSWER: Possible Cause: alloantibody Resolution: Identify antibody. Xmatch units neg for corresponding antigen 2 week deferral - CORRECT ANSWER: measles (rubeola), mumps, polio, typhoid, yellow fever vaccines 4 week deferral - CORRECT ANSWER: rubella, chicken pox (varicella zoster) vaccine 76-year-old female diagnosed with urosepsis was transfused 2 units of packed red blood cells. Her type was AB positive with a negative antibody screen. The units transfused were AB positive. Upon receiving the second unit, the patient became hypoxic with tachypnea. The clerical check was acceptable and DAT negative. She received 269 mL from the second unit before a reaction was called. Her temperature fell from 38°C to 36.4°C, her pulse increased from 72 to 90, and respirations rose from 35 to 41. Her BP was 110/70. The patient expired approximately 12 hours from the time the reaction was called. What type of reaction was most likely present? A. Febrile B. Symptoms not related to transfusion C. Allergic D. TRALI - CORRECT ANSWER: B This case emphasizes the statistic that not all causes of death are related to transfusion. The temperature dropped ruling out a febrile reaction; there was no evidence of pulmonary edema or hypotension seen with TRALI (and plasma products are more associated with TRALI than red cells); and there was no sign of hives or itching, which are often associated with an allergic reaction 95% confidence interval - CORRECT ANSWER: p value < 0>