1. A neonate is prescribed a medication that is known to be extensively metabolized by the liver. Considering the neonate's immature hepatic system, what adjustment should be made to the medication regimen? - A) Increase the dosage to ensure therapeutic levels. - B) Decrease the dosage to prevent toxicity. - C) Administer the medication intravenously. - D) No adjustment is necessary. Correct Answer: B) Decrease the dosage to prevent toxicity. Rationale: Neonates have immature liver enzymes, which can lead to decreased metabolism of medications. Therefore, dosages often need to be reduced to prevent drug accumulation and toxicity. 2. A preterm infant is exhibiting signs of apnea of prematurity. Which pharmacological agent is considered first-line treatment for this condition? - A) Caffeine citrate - B) Theophylline - C) Doxapram