Both men and women experience bone loss with aging. The bones most likely to demonstrate significant loss are: 1. Cortical bones 2. Femoral neck bones 3. Cervical vertebrae 4. Pelvic bones - ANSWER 2. Femoral neck bones Bisphosphonates treat or prevent osteoporosis by: 1. Inhibiting osteoclastic activity 2. Fostering bone resorption 3. Enhancing calcium uptake in the bone 4. Strengthening the osteoclastic proton pump - ANSWER 1. Inhibiting osteoclastic activity Prophylactic use of bisphosphonates is recommended for patients with early osteopenia related to longterm use of which of the following drugs? 1. Selective estrogen receptor modulators