Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? Phentermine and Diethylpropion How does Phentermine and Diethylpropion promote weight loss? -Promote weight loss by decreasing appetite -They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability of norepinephrine at receptors in the brain What is the maximum recommended duration of use for non-amphetamines? 3 months or less What drug schedule are Phentermine and Diethylpropion under? Schedule IV What labs should be monitored with Phentermine and Diethylpropion? What condition should we screen for? -baseline CMP (watch electrolytes and creatinine) -screen for depression Phentermine adverse effects -increase HR and BP -dry mouth and constipa