1. Systemic lupus erythematosus (SLE) is a: Answer chronic and progressive autoimmune disorder in which inflammatory and immune attacks occur against multipleself tissues and organs. Over time the progressive loss of tissue integrity through excessive inflammationand overactive immunity leads to organ failure and death. 2. Triggers for expression of SLE in a genetically susceptible adult includeAnswer infection, injury, drugs, hormones, and exposure to environmental substances, especially ultraviolet (UV) light 3. Involved in the symptoms and tissue damage caused by SLE: Answer innate andspecific immune reactions 4. Causes a type III hypersensitivity reaction with formation of immune complexes that precipitate and deposit in various tissues: Answer when circulating autoantibodies attack tissues 5. Although progressive in nature and chronic, symptoms may be present at a: Answer constant level, at a reduced level (remission), or as an acute episode ofincreased symptoms known as a "flare" or exacerbation. 6. Onset of SLE: Answer slow and the symptoms may be so mild, general, and vague thatdiagnosis often is difficult and delayed The average time from initial mild symptoms to actual diagnosis is 6 years