1. Leukemia is a general term used to describe: Answer a group of cancers affecting the blood and the blood forming tissues of the -bone marrow -lymph system -spleen -accumulation of dysfunctional cells due to loss of regulation in cell division -fatal if untrateds 2. Leukemia occurs in all: Answer age groups 3. There is no single cause of leukemia it is a: Answer combo of genetic and environmental influences -begin with mutation in DNA -Oncogenes or abnormal genes cause many types of cancers -Chemical agents, chemotherapuetic agents, virsuses, radiation, and immunologic deficiencies that can also cause cancer 4. Leukemia is is classified based on: Answer acute or chronic which refers to cell maturity and nature of disease onset 5. Acute leukemia is characterized by the: Answer clonal proliferation of immature hematopoietic cells -leukemia develops following malignant transformation of a single type of immature hematopoietic cell, followed by cellular replication and expansion of that malignant clone