1. Which of the following statements best describes pharmacokinetics?
a) The study of how drugs affect the body
b) The study of how the body absorbs, distributes, metabolizes, and
excretes drugs
c) The study of how drugs interact with each other and with other
substances
d) The study of how drugs are used to treat, prevent, or diagnose diseases
Answer: B. Pharmacokinetics is the study of how the body handles drugs,
including absorption, distribution, metabolism, and excretion.
Pharmacodynamics is the study of how drugs affect the body,
pharmacology is the study of drugs in general, and pharmacotherapeutics
is the study of how drugs are used for therapeutic purposes.
2. What is the difference between a drug's bioavailability and its
bioequivalence?
a) Bioavailability is the fraction of a drug that reaches the systemic
circulation, while bioequivalence is the similarity between two
formulations of the same drug in terms of bioavailability and
pharmacological effects
b) Bioavailability is the extent to which a drug produces its intended
effects, while bioequivalence is the equivalence between two formulations
of the same drug in terms of safety and efficacy
c) Bioavailability is the rate at which a drug is absorbed into the
bloodstream, while bioequivalence is the degree to which two
formulations of the same drug have the same pharmacokinetic parameters
d) Bioavailability is the concentration of a drug in the blood or tissues,
while bioequivalence is the interchangeability between two formulations
of the same drug in terms of dosage and administration
Answer: A. Bioavailability is the fraction of a drug that reaches the
systemic circulation after administration, which can be affected by factors
such as absorption, first-pass metabolism, and protein binding.
Bioequivalence is the similarity between two formulations of the same
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