1. What is the primary purpose of conducting a randomized controlled trial (RCT) in clinical research? A. To test the efficacy of health interventions B. To determine the cost-effectiveness of treatments C. To assess the prevalence of diseases D. To evaluate patient satisfaction with care Correct Answer: A Rationale: RCTs are considered the gold standard for testing the efficacy of health interventions because they utilize randomization to minimize bias, allowing for a clearer understanding of the intervention's true effects. 2. In the context of evidence-based practice, what does the term 'PICO' stand for? A. Population, Intervention, Comparison, Outcome B. Problem, Information, Collaboration, Outcome C. Population, Investigation, Community, Observation D. Problem, Intervention, Comparison, Observation