1. Which of the following statements accurately describes

pharmacogenetics?

a) It refers to the study of how genetic differences influence

an individual's response to medications.

b) It involves the study of how the environment affects the

efficacy of medications.

c) It focuses on the development of new pharmaceutical

drugs based on genetic factors.

d) It investigates the side effects of medications on

different populations.

Answer: a) It refers to the study of how genetic differences

influence an individual's response to medications.

Rationale: Pharmacogenetics explores the genetic

variations that affect an individual's response to drugs,

allowing for personalized medicine based on genetic

makeup.

2. Cytochrome P450 enzymes are the most significant

enzymes involved in drug metabolism. Which of the

following CYP enzymes is responsible for metabolizing

approximately half of all medications?

a) CYP1A2

b) CYP2C9

c) CYP2D6

d) CYP3A4