Zidovudine (retrovir)-

○ Non-nucleoside reverse transcriptase inhibitor

■ Only one can be given IV intrapartum (need for this based on viral

load) → considered drug of choice in pregnancy

○ Penetrates CSF

○ Adverse effects:

■ Hematologic toxicity

● Hold for Hgb below 5 gm/dL or 25% drop from baseline

● Hold for neutrophil count below 750 cells/mL

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Category NURS EXAM
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