Answer:
Dopamine
Obsessive-compulsive disorder (OCD) is linked to defects in the cortico-striatal-thalamic-cortical (CSTC)
circuitry, which may be linked to neurotransmitter dysregulation throughout this network. Serotonin,
dopamine, glutamate, and -aminobutyric acid (GABA) are the main neurotransmitters throughout the
CSTC.
Compulsive behaviors linked to OCD are likely the product of a related dopaminergic reward
system dysfunction. Continuous ventral striatum activation may lead to an undirected expectation of
reward. Anxiety and a desire to fill the gap are caused by unfulfilled expectations.
Step-by-Step explanation
References
Richter, M. A., De Jesus, D. R., Hoppenbrouwers, S., Daigle, M., Deluce, J., Ravindran, L. N., ... &
Daskalakis, Z. J. (2019). Evidence for cortical inhibitory and excitatory dysfunction in obsessive
compulsive disorder. Neuropsychopharmacology, 37(5), 1144-1151.
Pittenger, C., Krystal, J. H., & Coric, V. (2016). Glutamate-modulating drugs as novel
pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. NeuroRx, 3(1), 69-81.
1 points
QUESTION 2
1. Select the class of drugs most effective in treating pain disorder.
Answer:
A
Opioid analgesics
.
B TCA and SSRI
. antidepressants
C Beta-adrenergic
. blockers
D
Mood stabilizers
.
Opioids analgesics
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