what are the 2 conditions under the inflammatory bowel disease umbrella? 1. ulcerative colitis 2. crohn's dz in comparing ulcerative colitis and crohn's dz, which is: -limited to the colon w/ rectum always involved VS mouth to anus -transmural VS mucosa/submucosa involved -LLQ VS RLQ pain -bloody diarrhea VS non -complications of perianal dz, strictures, fistulas & granulomas VS colon cancer & toxic megacolon -colonoscopy showing "skip lesions" & cobblestoning VS ulceration & pseudopolyps -barium studies showing "stovepipe sign" (loss of haustral markings) VS "string sign" narrowing through scarred areas -(+)P-ANCA VS (+)ASCA (anti saccharomyces cerevisiae Ab) -curative VS noncurative 1. ulcerative colitis- colon/rectum, mucosa/submucosa, LLQ pain, bloody diarrhea, comps of colon cancer & toxic megacolon, colonoscopy w/ ulcerations & pseudopolyps, "stovepipe sign" (loss of haustral markings), (+)P-ANCA, curative 2. crohn's dz- mouth to anus, transmural, RLQ pain, nonbloody diarrhea, comps of perianal dz, strictures, fistulas, granulomas, "skip lesions" & "cobblestoning", "string sign", (+)ASCA, noncurative what are the best studies of choice for ulcerative colitis vs crohn's dz in acute dz? -UC: flex sigmoidoscopy in acute dz (colonoscopy and barium enema CONTRAINDICATED in acute dz bc can cause perf or toxic megacolon) -crohn's dz: upper GI series (barium swallow) in acute dz what medications are used to treat ulcerative colitis and crohn's dz? 1. 5-aminosalicylic acids (anti-inflammatory) oral mesalamine best for maintenance, topical mesalamine (rectal suppositories & enemas), sulfasalzine (give w/ folic acid); all of these work best in the colon- so are better for tx'ing UC