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1. A patient with asthma is prescribed a beta2-agonist. Which
pharmacodynamic principle explains the bronchodilation effect?
A. Receptor theory
B. Drug-receptor interaction
C. Dose-response relationship
D. Drug metabolism
Answer: B. Drug-receptor interaction
Rationale: Beta2-agonists work by binding to beta2-adrenergic receptors
on the smooth muscle cells of the airways, leading to bronchodilation.
2. Which term describes the magnitude of maximal response that can be
produced from a particular drug?
A. Potency
B. Efficacy
C. Therapeutic index
D. Bioavailability
Answer: B. Efficacy
Rationale: Efficacy refers to the inherent ability of a drug to produce a
maximal response.
3. What does the term 'agonist' refer to in pharmacology?
A. A drug that blocks receptor activity
B. A drug that enhances receptor activity
C. A drug that has no effect on receptor activity
D. A drug that reduces the metabolism of another drug
Answer: B. A drug that enhances receptor activity
Rationale: An agonist is a substance that binds to a receptor and
activates it, producing a physiological response.
4. In the context of pharmacodynamics, what does 'affinity' refer to?
A. The rate at which a drug is eliminated from the body
B. The strength of binding between a drug and its receptor
C. The ability of a drug to pass through cell membranes
D. The degree to which a drug causes side effects
Answer: B. The strength of binding between a drug and its receptor
Rationale: Affinity is the measure of how tightly a drug binds to its
receptor.
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