1. What is the primary neurotransmitter implicated in the pathophysiology of Bipolar Disorder? A. Serotonin B. Dopamine C. GABA D. Glutamate Answer: B. Dopamine Rationale: Dopamine dysregulation is often associated with the manic phases of Bipolar Disorder, influencing mood regulation and reward-seeking behavior. 2. Which of the following is a common cognitive symptom of Major Depressive Disorder? A. Grandiosity B. Decreased need for sleep C. Difficulty concentrating D. Increased goal-directed activity Answer: C. Difficulty concentrating Rationale: Cognitive symptoms such as difficulty concentrating, indecisiveness, and slowed thinking are characteristic of Major Depressive Disorder. 3. Lithium is a well-known mood stabilizer used in the treatment of Bipolar Disorder. What is a crucial consideration for its use?