Test Bank to accompany Psychopharmacology, Third Edition Meyer • Quenzer Chapter 1: Principles of Pharmacology Multiple Choice 1. refer(s) to specific molecular changes that occur when a drug binds to a particular target site or receptor, while are the resulting widespread alterations in function. a. Drug action; therapeutic effects b. Side effects; drug effects c. Therapeutic effects; side effects d. Drug action; drug effects Answer: d Textbook Reference: Pharmacology: The Science of Drug Action 2. After drug administration has occurred, the amount of drug in the blood that is free to bind at specific target sites is referred to as a. the therapeutic dose. b. first-pass effects. c. bioavailability. d. ED50. Answer: c Textbook Reference: Pharmacokinetic Factors Determining Drug Action 3. The specific molecular changes that occur when a drug binds to a particular target site or receptor are referred to as a. drug effects. b. drug action. c. side effects. d. placebo effects. Answer: b Textbook Reference: Pharmacology: The Science of Drug Action 4. Which of the following is not a possible explanation for placebo effects? a. Pavlovian conditioning b. Genetic variation c. Drug competition d. Expectation of outcome Answer: c Textbook Reference: Pharmacology: The Science of Drug Action WWW.THENURSINGMASTERY.COM Page 2 of 247 5. The administration of oxytocin has been proposed as a treatment for autism. a. intravenous b. oral c. intranasal d. intracerebral Answer: c Textbook Reference: Pharmacokinetic Factors Determining Drug Action 6. Which factor does not affect the pharmacokinetics of a drug? a. Route of administration b. Lipid solubility c. Depot binding