USMLE Step 2 CK High-Yield Questions and Answers
Latest 2025/2026 with complete solution
Classic EKG finding in atrial flutter - ANSWER"Sawtooth" p waves
Definition of unstable angina - ANSWERAngina that is new, is worsening, or occurs at
rest
Antihypertensive for a diabetic patient with proteinuria - ANSWERACEI
Beck's triad for cardiac tamponade - ANSWERHypotension, distant heart sounds, and
JVD
Drugs that slow heart rate - ANSWERBeta-blockers, CCBs, digoxin, amiodarone
Hypercholesterolemia treatment that leads to flushing and pruritus - ANSWERNiacin
Murmur - hypertrophic obstructive cardiomyopathy - ANSWERA systolic ejection
murmur heard along the lateral sternal border that increases with decreased preload
(i.e. Valsalva maneuver)
Murmur - aortic insufficiency - ANSWERAustin Flint murmur, a diastolic, decrescendo,
low-pitched, blowing murmur that is best heard sitting up; increases with increased
afterload (i.e. handgrip)
Murmur - aortic stenosis - ANSWERA systolic crescendo/decrescendo murmur that
radiates to the neck; increases with increased preload (i.e. squatting)
Murmur - mitral regurgitation - ANSWERA holosystolic murmur that radiates to the
axillar; increases with increased afterload (handgrip)
Murmur - mitral stenosis - ANSWERA diastolic, mid to late, low-pitched murmur
preceded by an opening snap
Treatment for atrial fibrillation and atrial flutter - ANSWERIf unstable, cardiovert. If
stable or chronic, rate control with CCBs or beta-blockers
Treatment for ventricular fibrillation - ANSWERImmediate cardioversion
Dressler's syndrome - ANSWERAn autoimmune reaction with fever, pericarditis and
increased ESR occurring 2-4 weeks post-MI
IV drug use with JVD and holosystolic murmur at left sternal border. Treatment? -
ANSWERTreat existing heart failure and replace tricuspid valve