ADVANCED PATHOPHYSIOLOGY EXAM 1 NEWEST 2024 ACTUAL EXAM 200 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A+

ADVANCED PATHOPHYSIOLOGY EXAM 1
NEWEST 2024 ACTUAL EXAM 200 QUESTIONS
AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY
GRADED A+
Which of the following is not characteristic of cellular dysplasia?
a. variation in size and shape of cells
b. small, pale nuclei
c. disorderly arrangement of cells
d. preneoplastic change - ANSWER- B
If a normal individual began to take cortisol 100 mgs. every day as a medication,
which of the following would result?
a. hypertrophy of the adrenal gland
b. hyperplasia of the adrenal gland
c. atrophy of the adrenal gland
d. hypertrophy and hyperplasia of the adrenal gland - ANSWER- C
If a normal individual began to take thyroid hormone 100 mcgs. every day as a
medication, which of the following would result?
a. hypertrophy of the thyroid gland
b. hyperplasia of the thyroid gland
c. atrophy of the thyroid gland

d. hypertrophy and hyperplasia of the thyroid gland - ANSWER- B
Chronic alcoholism can result in the development of a fatty liver because it results
in which of the following?
a. increased production of free fatty acids
b. increased conversion of free fatty acids to triglycerides
c. decreased oxidation of cholesterol, triglycerides, and phospholipids
d. decreased binding of cholesterol, triglycerides, and phospholipids to apoproteins
- ANSWER- A
Which of the following is the primary difference between wet and dry gangrene?
a. Infection and inflammation are present in wet gangrene.
b. Wet gangrene results from arterial occlusion and dry gangrene from venous
stasis.
c. Dry gangrene involves the presence of Clostridium perfringens.
d. Wet gangrene occurs only in internal organs. - ANSWERWhich of the following components is not involved in apoptosis?
a. Bcl-2
b. apaf-1
c. caspase 9
d. cytochrome c
e. HLA 2 - ANSWER- E
Some cancer-causing viruses are able to protect the cells that they transform from
undergoing apoptosis by interfering with the action of the apoptosis promoter
called:

a. TNF-alpha.
b. Fas.
c. p53.
d. IL-2.
e. INF-beta. - ANSWER- C
Which of the following diseases is thought to be related to free radical damage?
a. osteoarthritis
b. detached retina
c. cerebral aneurysm
d. cancer - ANSWER- D
Which of the following enzymes, released from dying cells, may indicate problems
in the liver?
a. alanine aminotransferase
b. aspartate aminotransferase c. alkaline phosphatase
d. all of the above
e. none of the above - ANSWER- D
Researchers hypothesize that the disappearance of dopamine-generating cells in the
midbrain in Parkinson's Disease may be related to oxidative stress due to a
decrease in the amount of glutathione in the midbrain. The best explanation for this
theory is which of the following?
a. DNA synthesis requires glutathione for optimal development.
b. Dopamine synthesis requires glutathione to prevent free radical production.
c. Free radicals produced via dopamine synthesis are neutralized by glutathione.

d. Glutathione is needed for entry of dopamine into the cerebral circulation. -
ANSWER- C
Which of the following is(are) true regarding aging?
a. may involve an increase in autoantibodies
b. may result from damage accumulation
c. both are true
d. neither is true - ANSWER- C
In theories of aging, cross-linking implies which of the following?
a. The lifespan and number of times a cell can replicate are preprogrammed.
b. The number of cell doublings is limited.
c. There is oxygen toxicity.
d. Cell permeability decreases. - ANSWER- D
Etiology - ANSWER- Causative factors in a particular disease
Iatrogenic - ANSWER- produced by treatment
Epidemiology - ANSWER- risk factors and distribution in populations
Incidence - ANSWER- number of new cases
Prevalence - ANSWER- number of existing cases both new and old
clinical manifestations - ANSWER- signs, symptoms, and diagnostic criteria

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