1. A patient is prescribed a medication that has a half-life of 8 hours. If the initial dose was 200mg, how much of the drug would remain in the body after 24 hours? - A) 100mg - B) 50mg - C) 25mg - D) 12.5mg Answer: C) 25mg Rationale: The half-life of a drug is the time it takes for the plasma concentration of a drug to reduce to half its original value. After one halflife (8 hours), 100mg would remain. After the second half-life (16 hours), 50mg would remain. After the third half-life (24 hours), 25mg would remain. 2. A medication order calls for 1g of cefazolin to be administered intravenously. The medication is available in a concentration of 250mg/mL. How many milliliters will you administer? - A) 2 mL - B) 4 mL - C) 6 mL - D) 8 mL Answer: B) 4 mL Rationale: To find the volume required to deliver the dose, divide the ordered dose (1000mg or 1g) by the concentration (250mg/mL). This gives 4mL. 3. Calculate the drip rate for 1 L of 0.9% NaCl IV to be infused over 8 hours. The drop factor is 15 drops/mL. - A) 31 drops/min - B) 125 drops/min - C) 62 drops/min - D) 250 drops/min Answer: A) 31 drops/min Rationale: To calculate the drip rate, divide the total volume (1000mL) by the total time in minutes (480 minutes for 8 hours). This gives approximately 2.08mL/min. Multiplying this by the drop factor (15 drops/mL) gives a drip rate of 31.2 drops/min, which is rounded down to