Chapter 11: Mechanisms of Microbial Genetics
* = Correct answer
Multiple Choice
1. Gene expression includes which of the following?
A. DNA replication
B. replication, transcription, and translation
C. transcription and translation*
D. translation only
Difficulty: Easy
ASM Standard: N/A
2. The central dogma describes which of the following?
A. the process by which enzymes are modified after translation
B. the steps of gene expression*
C. the way DNA is replicated
D. the way RNA is used as a template to make DNA
Difficulty: Easy
ASM Standard: N/A
3. During bacterial DNA replication, which of the following holds open the replication bubble?
A. DNA polymerases
B. helicases
C. primers
D. single-strand binding proteins*
Difficulty: Easy
ASM Standard: N/A
4. Telomeres found in which of the following?
A. all microbes
B. animal cells only, not in unicellular organisms
C. fungal, protist, plant, and animal chromosomes*
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Chapter 11: Mechanisms of Microbial Genetics
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D. microbes only, including all domains
Difficulty: Easy
ASM Standard: 16
5. Which of the following best describes the direction in which lagging strands are added?
A. as 5′ to 3′ Okazaki fragments in an overall 3′ to 5′ direction only*
B. as 5′ to 3′ Okazaki fragments in an overall 5′ to 3′ direction only
C. in the 3′ to 5′ or 5′ to 3′ direction
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Chapter 11: Mechanisms of Microbial Genetics
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D. in variable directions depending on the species
Difficulty: Easy
ASM Standard: N/A
6. Which of the following correctly describes uracil and where is it found?
A. It is a nitrogenous base found in DNA and RNA.
B. It is a nitrogenous base found in DNA only.
C. It is a nitrogenous base found in RNA only.*
D. It is a nitrogenous base found only in nucleotides of molecules other than RNA and DNA.
Difficulty: Easy
ASM Standard: N/A
7. Which of the following is another name for the template strand (the strand of DNA that is
transcribed)?
A. anticodon strand
B. antisense strand*
C. sense strand
D. transcription strand
Difficulty: Moderate
ASM Standard: N/A
8. Which of the following correctly describes events that occur during transcription?
A. DNA polymerase binds to the site of initiation.
B. RNA polymerase binds to the core enzyme.
C. RNA polymerase binds to the operator.
D. RNA polymerase binds to the promoter.*
Difficulty: Easy
ASM Standard: N/A
9. Which of the following correctly explains why DNA replication is described as
semiconservative?
A. Each daughter strand contains one old strand and one new strand.*
B. Each daughter strand contains two new strands.
C. The nucleotides used in replication are recycled multiple times.
D. The nucleotides used in replication contain old and new components.
Difficulty: Moderate
ASM Standard: N/A
10. During DNA replication in bacteria, which of the following enzymes adds DNA nucleotides
to the growing strand?
A. DNA polymerase I
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