1. Which of the following are the reasonsfor increased practice of compounding patientspecific medications? SATA a. Many patients need drug dosages or strengths that are not commercially available b. Many patients need dosage forms, such as suppositories, oral liquids or topicals that are not commercially available c. Many patients are allergic to excipientsin commercially available products d. gumdrops, popsicles and lollipops e. Some medications are not very stable and require preparation and dispensing every few days; they are not suitable to be manufactured products. 2. Which of the following factors are related to drug particle size with oral dosage form? SATA a. Uniformity of drug dosage content in each dosage form unit b. Properties such as taste, color, and texture of the medicine c. Bioavailability d. Flow rates of powder mixtures in manufacture machines e. Drug dissolution rate 3. Which of the following statementsis/are true about drug product recall? SATA a. If a marketed product presents a threat or a potential threat to consumer safety, that product may be recalled orsought for return to the manufacturer from its depth of distribution b. The pharmaceutical manufacturer islegally bound to report serious unlabeled adverse reactions to the FDA c. A practitioner has a responsibility to report a problem with any drug product or medical device d. Reported problems may include product defects, product adulteration, container leakage, improper labeling, and unexpected adverse reactions 4. If the half-life for decomposition of a drug is 12 hours how long (in hours) would it take for 500 mg of the drug to decompose by 10%? Assuming first order kinetics and at a constant temperature (Answer must be numeric; round the final answer to the nearest whole number): a. 2 hours 5. If the amount of drug in the body declines from 100% of the dose (IV bolus injection) to 90% of the dose in 48 hours, what is the elimination half-life for this drug (in hours)? Assume first-order kinetics. (Answer must be numeric; round the final answer to the nearest whole number):