What drugs should be avoided with Kava Kava? - Alprazolam CNS depressants (e.g., phenobarbital, zolpidem) Cultural Formulation Interview perform what 3 functions? - Clarify meaning of illness Empower the patient Validate symptoms within cultural context What does a cultural formulation interview do? - cultural assessment What is the normal range for TSH? - 0.5 - 5.0 mu/L What are lab values in Hyperthyroidism - Decreased TSH Increased T4 and T3 What are labs in Hypothyroidism? - Increased TSH Decreased T4 and T3 What are 5 primary symptoms of Hyperthyroidism? - Heat intolerance Agitation, Anxiety, Irritability Tachycardia Mood swings Weight loss What are 4 primary symptoms of Hypothyroidism? - Cold intolerance Lethargy Weight gain Decreased libido Hypothyroidism mimics symptoms of what psychiatric disorder? - Depression Hyperthyroidism mimics symptoms of what psychiatric disorder? - Mania Valproic acid produces what teratogenic effect? - Spina bifida (neural tube defect) What is the primary organ where valproic acid is toxic? - Liver (hepatoxicity) What are 4 signs of hepatoxicity? - Abdominal pain in the URQ Reddish-brown urine Yellowing of the skin and sclera Fatigue Abdominal pain in the URQ, Reddish-brown urine, Yellowing of the skin and sclera, and Fatigue are signs of - Hepatoxicity What is the therapeutic range for valproic acid? - 50-125 mcg/ml What is a toxic level of valproic acid? - >150 mcg/ml What are 4 signs of valproic acid toxicity? - Disorientation Lethargy Respiratory depression Nausea/vomiting Disorientation, Lethargy, Respiratory depression, and Nausea/vomiting are symptoms of toxicity with what drug? - Valproic acid With suspected toxicity with valproic acid, what labs should be drawn? - DC drug Check drug level Obtain LFTs Obtain ammonia level What is the major side effect with Kava Kava? - Liver damage What herbal supplement is sued for anxiety, stress, and insomnia? - Kava Kava What are 5 symptoms of Stephen's Johnson Syndrome? - Fever Body aches Severe red rash Peeling skin Facial and tongue swelling Severe red rash, Fever, Body aches, Peeling skin, and Facial and tongue swelling are symptoms of - Stephen's Johnson Syndrome Which mood stabilizer causes the least weight gain? - Lamotrigine (Lamictal)