MLT ASCP EXAM LATEST ACTUAL EXAM 250 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A

MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM

250 QUESTIONS AND CORRECT DETAILED ANSWERS

WITH RATIONALES (VERIFIED ANSWERS)

|ALREADY GRADED A

The process of formation and development of blood cells is termed:

a. Hematopoiesis

b. Hematemesis

c. Hematocytometry

d. Hematorrhea - ANSWER- a. Hematopoiesis

During the second trimester of fetal development, the primary site of

blood cell production is:

a. Bone marrow

b. Spleen

c. Lymph nodes

d. Liver - ANSWER- d. Liver

Which of the following organs is responsible for the maturation of T

lymphocytes and regulation of their expression of CD4 and CD8?

a. Spleen

b. Liver

c. Thymus

d. Bone marrow - ANSWER- c. Thymus

The best source of active bone marrow from a 20-year-old would be:

a. Iliac crest

b. Femur

c. Distal radius

d. Tibia - ANSWER- a. Iliac crest

Physiologic programmed cell death is termed:

a. Angiogenesis

b. Apoptosis

c. Aneurysm

d. Apohematics - ANSWER- b. Apoptosis

Which organ is the site of sequestration of platelets?

a. Liver

b. Thymus

c. Spleen

d. Bone marrow - ANSWER- c. Spleen

Which one of the following cells is a product of the CLP?

a. Megakaryocyte

b. T lymphocyte

c. Erythrocyte

d. Granulocyte - ANSWER- b. T lymphocyte

What growth factor is produced in the kidneys and is used to treat

anemia associated with kidney disease?

a. EPO

b. TPO

c. G-CSF

d. KIT ligand - ANSWER- a. EPO

Which one of the following cytokines is required very early in the

differentiation of a hematopoietic stem cell?

a. IL-2

b. IL-8

c. EPO

d. FLT3 ligand - ANSWER- d. FLT3 ligand

Hematopoietic stem cells produce all lineages of blood cells in sufficient

quantities over the lifetime of an individual because they:

a. Are unipotent

b. Have the ability of self-renewal by asymmetric division

c. Are present in large numbers in the bone marrow niches

d. Have a low mitotic potential in response to growth factors -

ANSWER- b. Have the ability of self-renewal by asymmetric division

Which of the following is an erythrocyte progenitor?

a. Pronormoblast

b. Reticulocyte

c. CFU-E

d. Orthochromic normoblast - ANSWER- c. CFU-E

Which of the following is the most mature normoblast?

a. Orthochromic normoblast

b. Basophilic normoblast

c. Pronormoblast

d. Polychromatic normoblast - ANSWER- a. Orthochromic normoblast

Which of the following is not related to the effects of erythropoietin?

a. The number of divisions of a normoblast

b. The formation of pores in sinusoidal endothelial cells for marrow

egress

c. The time between mitoses of normoblasts

d. The production of antiapoptotic molecules by erthroid progenitors -

ANSWER- b. The formation of pores in sinusoidal endothelial cells for

marrow egress

Hypoxia stimulates RBC production by:

a. Inducing more pluripotent stem cells into erythroid lineage