It is an estimate of the benefit of treatment under ideal conditions It is an estimate of the reduction of disease in treated groups • The generalizability of the study is increased • Reduces the potential for selection bias in allocation of treatment group • R&omized clinical trial with stratified r&omization • R&omization was successful since the investigators did not alter the selection of participants in either group in order to ensure equal percentages of men Question 1 Which of the following statements best describe efficacy? Question 2 A study is conducted for a pharmaceutical agent that has shown promise for reducing heart diseaseamong women. In order to more fully test the agent, an additional study is done restricting the participants to be r&omized to those who have a history of hypertension. Which of the following advantages cannot be claimed by the researchers? Question 3 What is the main advantage of the r&omization of the 168 study participants to one of the two drug treatment groups?

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