1. A 55-year-old male is diagnosed with hypogonadism and prescribed testosterone replacement therapy. Which of the following is an appropriate indication for testosterone therapy? A. Osteoporosis B. Erectile dysfunction C. Decreased muscle mass D. All of the above Answer: D. All of the above Rationale: Testosterone replacement therapy can help improve symptoms such as low bone density, erectile dysfunction, and decreased muscle mass in men with hypogonadism. 2. Which of the following is a contraindication for testosterone replacement therapy? A. Prostate cancer B. Hypertension C. Diabetes D. Obesity Answer: A. Prostate cancer Rationale: Testosterone therapy is contraindicated in men with prostate cancer due to the potential stimulation of tumor growth. 3. Monitoring of testosterone levels is important during therapy to prevent which of the following complications? A. Hypertension B. Suppression of spermatogenesis C. Osteoporosis D. Erectile dysfunction Answer: B. Suppression of spermatogenesis Rationale: Testosterone therapy can suppress endogenous testosterone production, leading to infertility in men. 4. Which of the following is an appropriate route of administration for testosterone replacement therapy? A. Oral tablets B. Intramuscular injection C. Transdermal patch D. Subcutaneous implant