1. Pathogenesis: Answer The development of the disease or the sequence of events involved in the tissue changes related to the specific disease process. 2. Onset: Answer sudden OR acute- An acute disease indicates a short-term illness that develops quickly with marked signssuch as high fever orsevere pain—for example, acute appendicitis; onset may be insidious, best described as a gradual progression with only vague or very mild signs. 3. Chronic: Answer often a milder condition developing gradually,such asrheumatoid arthritis, but it persistsfor a long time and usually causes more permanent tissue damage. Often a chronic disease is marked by intermittent acute episodes. 4. Subclinical (stage/phase): Answer in which pathologic changes occur but the patient exhibits no obvious manifestations, perhaps because of the great reserve capacity of some organs. 5. Latent stage: Answer "silent" stage, in which no clinical signs are evident, characterizes some diseases. In infectious diseasesthisstage may be referred to asthe incubation period, which is the time between exposure to the microorganism and the onset of signs orsymptoms; it may last for a day orso or may be prolonged, perhapsfor days or weeks. 6. Disease transmission of an insect bite: Answer The injury occurs when the insect either bites or stings the patient.Venom is injected into the tissue, resulting in the body's response to a foreign protein. 7. Rocky Mountain Spotted Fever/Tick Bite disease transmission: Answer The causative agent, Rickettsia rickettsii, is transmitted by the wood tick and is