Chapter 1 - Cellular Biology 3 Chapter 2 - Altered Cellular and Tissue Biology Environmental Agents 16 Chapter 3 - The Cellular Environment Fluids and Electrolytes Acids and Bases 28 Chapter 4 - Genes and Genetic Diseases 41 Chapter 5 - Genes Environment-Lifestyle and Common Diseases 51 Chapter 6 - Epigenetics and Disease 59 Chapter 7 - Innate Immunity Inflammation 64 Chapter 8 - Adaptive Immunity 78 Chapter 9 - Alterations in Immunity and Inflammation 89 Chapter 10 - Infection 102 Chapter 11 - Stress and Disease 110 Chapter 12 - Cancer Biology 117 Chapter 13 - Cancer Epidemiology 129 Chapter 14 - Cancer in Children 135 Chapter 15 - Structure and Function of the Neurologic System 140 Chapter 16 - Pain Temperature Regulation Sleep and Sensory Function 151 Chapter 17 - Alterations in Cognitive Systems Cerebral Hemodynamics and Motor Function 165