1. **Multiple Choice:** Which of the following drug classes is known to have a positive inotropic effect on the heart? A) ACE inhibitors B) Beta-blockers C) Calcium channel blockers D) Cardiac glycosides **Correct Answer:** D) Cardiac glycosides **Rationale:** Cardiac glycosides such as digoxin are known for their positive inotropic effect on the heart, increasing the strength of cardiac contractions. 2. **Fill-in-the-Blank:** The mechanism of action of statins involves inhibition of the enzyme ________, which plays a key role in the synthesis of cholesterol. **Correct Answer:** HMG-CoA reductase **Rationale:** Statins work by inhibiting HMG-CoA reductase, an enzyme involved in the production of cholesterol in the liver. 3. **True/False:** Nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of gastrointestinal bleeding due to t