1. A 45-year-old female presents with a complaint of fatigue and weight gain. Which of the following diagnostic studies would be most appropriate to evaluate for hypothyroidism? A. Serum cholesterol test B. Thyroid-stimulating hormone (TSH) assay C. Complete blood count (CBC) Correct Answer: B Rationale: A TSH assay is the most sensitive test for hypothyroidism, as it can detect even mild cases when the thyroid gland is not producing enough hormones, which can lead to symptoms such as fatigue and weight gain. 2. When conducting a health history, which of the following pieces of information is most critical for assessing a patient's risk of coronary artery disease (CAD)? A. Family history of CAD B. Preference for salty foods C. Frequency of aerobic exercise