A patient with a recent diagnosis of acute renal failure has a long-standing

seizure disorder which has been successfully controlled for several years

with antiseizure medications. The nurse should recognize that the

patient's compromised renal function will likely

Response

Feedback:

Impaired renal function will increase the half-life of drugs that

are metabolized by the kidneys. This does not necessarily

render such medications ineffective and it does not decrease

the first-pass effect. IV administration will not compensate for

the patient's impaired renal function.

• Question 2

A patient is treated with an antibiotic for an infection in his leg. After 2

1 out of 1 points

days of taking the antibiotic, the patient calls the clinic and reports that he

has a rash all over his body. The nurse is aware that a rash can be an

adverse effect of an antibiotic and can be either a biologic, chemical, or

physiologic action of the drug, which is an example of

Response

Feedback

:

Pharmacodynamics is the biologic, chemical, and physiologic

actions of a particular drug within the body and the study of

how those actions occur, including adverse effects. It is how the

drug affects the body. The pharmacodynamics of a drug is

responsible for its therapeutic effects and sometimes its

adverse effects. Pharmacotherapeutics refers to the desired,

therapeutic effect of the drug. Pharmacokinetics is the changes

that occur to the drug while it is inside the body.

Pharmacogenetics is the study of how genetic variables affect

the pharmacodynamics of a drug in a specific patient.

• Question 3

A home health nurse notes that there have been changes to a patient's